5 Surprising Ways Magnesium Helps ADHD, Anxiety, OCD and Depression

Dr. Roseann Capanna-Hodge

Dr. Roseann Capanna-Hodge

Magnesium is the most used nutrient in the body and when you are stressed, you just can't get enough of it. By supplementing with magnesium, you not only calm the nervous system, you help your body combat stress and give what it needs to work at an optimal level and combat mental health symptoms.

There are many supplements that help to calm the brain and reduce stress. One of the most prominent natural anxiety supplements, Magnesium, is a cofactor in more than 300 enzyme systems that regulate diverse biochemical and enzymatic reactions within the body. Magnesium is required for its assistance with many chemical functions that support the central nervous system in managing stress. 

Since the majority of Western populations consume less than the recommended amount of magnesium, supplementation is often needed to support the brain and body

Types of Magnesium


There are seven different types of magnesium and each has a different effect on the body. 

  • magnesium chloride
  • magnesium sulfate
  • magnesium citrate
  • magnesium oxide
  • magnesium glycinate
  • magnesium orotate
  • magnesium L-threonate

You can take a magnesium supplement or you can take a magnesium salt bath or even do both. With so much stress in the world, we need a ton of magnesium to support the brain and body, so adding magnesium supplements is a simple way to improve cognitive function and get better sleep. 

7 Types of Magnesium illustration | Dr. Roseann


Magnesium Calms the Brain


Magnesium combats a stress activated nervous system that is in a “rev” state and less face it, stress affects the brain

When the nervous system is hyper stress activated and the brain reaches maximum capacity, the brain can only respond in three ways, fight, flight, or freeze. There are a variety of techniques that when consistently applied, help to lower the activation response. 

It all starts with reconnecting to the body and understanding the signals your body gives you before your brain goes into fight, flight or freeze. Understanding those somatic responses empowers a person to utilize tools to help calm their nervous system especially feeling frozen like with panic attacks. 

When you are in a fight, flight, or freeze state, you are in survival mode and your brain and it's heightened state is unable to fully process language, pay attention, or take action outside of survival. In other words, The brain and body‘s primary objective in this state is to reduce stress and that means ignoring most other stimuli and focusing on just getting through this stressful time. 

Magnesium is required for its assistance with many chemical functions that support the central nervous system in managing stress. And when we calm the brain, it allows for the mental capacity to do psychotherapy such as cognitive behavioral therapy and other therapies that focus on how to change your thoughts and actions. 

Magnesium Improves ADHD Behaviors


Research shows that people with Attention-Deficit Hyperactivity Disorder (ADHD) may have reduced levels of magnesium and other nutrients such as Vitamin D, ferritin, and zinc (Hemamy et al., 2020). In one study, after eight weeks of Vitamin D and magnesium supplementation, the blood levels of these nutrients increased significantly, which resulted in a significant decrease in conduct problems, social problems, and anxiety scores. 

When focus and alertness issues and other ADHD symptoms are present, the day to day life of children with ADHD and their families can be a challenge. The constant need for verbal reminders breaks down the parent-child relationship and leads to a whole lot of friction. 

The clinical and biochemical manifestations for those with Attention-Deficit Hyperactivity Disorder range from inattentive symptoms to hyperactive-impulsive ones. Some children are prone to hyperfocusing and difficulty with transitioning. Children with attention deficit face many challenges at home and school and parents need effective natural solutions. Cognitive enhancers such as magnesium supplementation or vitamin D supplmentmentation can lead to improved alertness. 

There is a significant correlation between magnesium deficient children and neurobehavioral disorders, such as ADHD and autism

Getting the brain to regulate is a key component of our BrainBehaviorReset™ Method and because the science is clear that with a stress activated nervous system, you simply can't pay attention. Calming the brain is a key component  to helping improve attention and magnesium is an effective way to do just that. Focusing on natural ADHD solutions is important for the developing brain.

Magnesium Improves Brain Chemicals that Help Anxiety, OCD, Depression, and ADHD


Magnesium plays an essential role in neurologic function, including involvement in neurotransmitter synthesis, nerve transmission and neuromuscular conduction. The body needs magnesium to create neurotransmitters and for those neurotransmitters to communicate or really work properly and we know just how important proper neurotransmitter function is for mental health. 

Magnesium is an important regulator of neurotransmitter signaling, especially for the neurotransmitters glutamate and GABA through modulating the activation of NMDA glutamate and GABA receptors.

Magnesium is needed for energy production, or what is referred to as mitochondrial function, and the glucose breakdown for energy (glycolysis). Brain energy (cerebral) metabolism is often associated with anxiety and social behavior.

Magnesium is required for the synthesis of DNA, RNA, and the antioxidant glutathione, which is a powerful antioxidant that supports detoxification and a healthy immune system. Oxidative stress and issues with poor detoxification are associated with increased levels of anxiety, as well as numerous mental health conditions. 

These actions serve to calm the brain, which decreases symptoms associated with clinical conditions such as anxiety, obsessive compulsive disorder, mood disorder, and attention-deficit hyperactivity disorder. 

There is an abundance of research that shows magnesium supplementation can improve symptoms across a variety of neurological and clinical conditions (Kirland et al., 2018). The surprising part for most people is that there are scientific studies that show just how effective magnesium supplementation can be in improving mental health and neurological conditions.

Magnesium Puts The Breaks on the Intrusive Thoughts 


In terms of neurotransmitters and mental health, magnesium inhibits the release of excitatory neurotransmitters and can increase feel good brain chemicals such as serotonin. For example, people with OCD have too many excitatory neurotransmitters that cause the brain to get stuck with an intrusive thought loop. 

Calming down those excitatory neurotransmitters gives someone with OCD enough room to employ the tools they learn in Exposure and Response Prevention (ERP) therapy

Magnesium Helps Reduce Anxiety


When we are stressed or anxious, it shows up as runaway thoughts and physically in a multitude of ways such as body tension, pain, difficulty sleeping, etc. Feelings of anxiety can be very overwhelming and not only affect brain function, but can wear the body and mind out and lead to depressive symptoms and even mood disorders.

A poster depicting the correlation between magnesium and mental health, with the words "neurotic soon" highlighted.
Ultimate Guide to Neurotransmitters

Studies suggest that magnesium helps different types of anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder and selective mutism, panic disorder, separation anxiety disorder, specific phobias, and helps to reduce physical and cognitive symptoms of anxiety. 

With the impact of extended periods of social isolation during the pandemic, social anxiety and anxiety-related difficulty in social situations is on the rise. Even the more extreme versions of social anxiety are increasing, as I have had more calls to our Ridgefield, CT center about selective mutism and anxiety symptoms in general,  in the last year than I have had in the last 5 years combined.

Magnesium plays an important role in the hypothalamic-pituitary-adrenocortical (HPA) axis to help manage the body's stress response system, as well as supports healthy neurotransmitter functioning. People with anxiety disorder need relief that doesn't have side effects and magnesium should be a part of everyone's toolkit.

You will read statements like, “magnesium cured my anxiety” but magnesium is just a tool in reducing anxiety symptoms. Don't get me wrong oral magnesium supplementation can result in a significant reduction of anxiety symptoms but the real work in in building a tolerance for stress and learning coping skills. 

How do I Know if I Need Magnesium?


With our stress-filled world, it is so easy to run low on the all important magnesium because it is so needed to help other body functions (more than three hundred!). 

There is a lot of research that shows the connection between low magnesium levels and clinical mental health conditions such as ADHD, anxiety, depression, and OCD. There is also research that helps us to understand symptoms seen with those with low magnesium levels.  

Symptoms of Magnesium Deficiency

  • Feeling stressed or anxious
  • Poor sleep quality
  • Difficulty getting to sleep
  • Have a diagnosed clinical mental health condition
  • Fatigue and muscle weakness
  • Poor appetite
  • Nausea
  • Muscle twitches and cramps
  • High blood pressure
  • Asthma
  • Irregular heartbeat
  • Osteoporosis 
  • Poor blood sugar control

 If you have any of these clinical issues, getting your magnesium levels tested is always a good idea. 

Just about anyone can benefit from magnesium supplementation through dietary supplements, creams and sprays, and bath salts, as well as eating magnesium rich foods  Ingested Magnesium is absorbed through the gut and absorption levels vary depending on a number of factors, including the health of the gut.

Magnesium can be combined with other supplements and herbs such as vitamin B6 for sleep and vitamin D for mental health for issues such as ADHD, mood and anxiety. 

The primary side effects of magnesium are loose stools, so it should be adjusted according to bowel tolerance. Always check with your provider before beginning any new health regime and note that your provider may want laboratory testing.


Black, L. J., Allen, K. L., Jacoby, P., Trapp, G. S., Gallagher, C. M., Byrne, S. M., & Oddy, W. H. (2015). Low dietary intake of magnesium is associated with increased externalising behaviours in adolescents. Public health nutrition, 18(10), 1824–1830. https://doi.org/10.1017/S1368980014002432

Hemamy, M., Heidari-Beni, M., Askari, G., Karahmadi, M., & Maracy, M. (2020). Effect of Vitamin D and Magnesium Supplementation on Behavior Problems in Children with Attention-Deficit Hyperactivity Disorder. International journal of preventive medicine, 11, 4. https://doi.org/10.4103/ijpvm.IJPVM_546_17

Kirkland, A. E., Sarlo, G. L., & Holton, K. F. (2018). The Role of Magnesium in Neurological Disorders. Nutrients, 10(6), 730. https://doi.org/10.3390/nu10060730

Rajizadeh, A., Mozaffari-Khosravi, H., Yassini-Ardakani, M., & Dehghani, A. (2017). Effect of magnesium supplementation on depression status in depressed patients with magnesium deficiency: A randomized, double-blind, placebo-controlled trial. Nutrition (Burbank, Los Angeles County, Calif.), 35, 56–60. https://doi.org/10.1016/j.nut.2016.10.014

Villagomez, A., & Ramtekkar, U. (2014). Iron, Magnesium, Vitamin D, and Zinc Deficiencies in Children Presenting with Symptoms of Attention-Deficit/Hyperactivity Disorder. Children (Basel, Switzerland), 1(3), 261–279. https://doi.org/10.3390/children1030261

Always remember… “Calm Brain, Happy Family™”

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Dr. Roseann is a Children’s Mental Health Expert and Therapist who has been featured in/on hundreds of  media outlets including, CBS, NBC, FOX News, PIX11 NYC, The New York Times, The Washington Post,, Business Insider, USA Today, CNET, Marth Stewart, and PARENTS. FORBES called her, “A thought leader in children’s mental health.” 

Dr. Roseann - Brain Behavior Reset Parent Toolkit

She is the founder and director of The Global Institute of Children’s Mental Health and Dr. Roseann Capanna-Hodge. Dr. Roseann is a Board Certified Neurofeedback (BCN) Practitioner, a Board Member of the Northeast Region Biofeedback Society (NRBS), Certified Integrative Medicine Mental Health Provider (CMHIMP) and an Amen Clinic Certified Brain Health Coach.  She is also a member of The International Lyme Disease and Associated Disease Society (ILADS), The American Psychological Association (APA), Anxiety and Depression Association of America (ADAA) National Association of School Psychologists (NASP), International OCD Foundation (IOCDF) International Society for Neurofeedback and Research (ISNR) and The Association of Applied Psychophysiology and Biofeedback (AAPB).

© Roseann-Capanna-Hodge, LLC 2023

Disclaimer: This article is not intended to give health advice and it is recommended to consult with a physician before beginning any new wellness regime. *The effectiveness of diagnosis and treatment vary by patient and condition. Dr. Roseann Capanna-Hodge, LLC does not guarantee certain results.

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